WoPPER - Webserver for Position Related data analysis of gene Expression in Prokaryotes - is a web-tool for the analysis of bacteria transcriptomic data. Gene expression is integrated with genomic annotations to reveal connections between transcription regulation and structural organization of bacterial genomes.
Both Microarray and RNA-seq data can be used as input for WoPPER. The analysis results include clusters of positionally proximal genes having the same trend of differential gene expression, along with graphical representations of the modulated clusters.
WoPPER is implemented in AngularJS, a structural framework for dynamic web applications, on the basis of the R-package PREDA, developed by Ferrari et al. in 2011 to identify regional variations in genomic data.